The pill can be taken without any restrictions on the timing of food or water, according to Lilly
For most people, combined oral contraceptives (the pill) fail for predictable reasons: missed doses, delayed starts, interacting medications (like certain anti-seizure drugs), or vomiting/diarrhea around the time of dosing
The trial randomized over 1,600 participants across the In both trials, all participants in the Foundayo treatment arms started the study at a dose of Foundayo 0.8 mg once-daily and then increased the dose in a step-wise approach at four-week intervals to their final randomized maintenance dose of 5.5 mg (via steps at 0.8 mg and 2.5 mg), 9 mg (via steps at 0.8 mg, 2.5 mg and 5.5 mg) or 17.2 mg (via steps at 0.8 mg, 2.5 mg, 5.5 mg, 9 mg and 14.5 mg)
Paterlini P & Brchot C (1994) Hepatitis B virus and primary liver cancer in hepatitis B surface antigen-positive and negative patients